6-chloro-1H-indole-3-carboxylic acid → (6-chloro-1H-indol-3-yl)-[4-(2-fluoro-phenyl)-piperidin-1-yl]-methanone
Reaction equation
[Cl:14][c:15]1[cH:16][cH:17][c:18]2[c:19]([C:24](=[O:25])[OH:26])[cH:20][nH:21][c:22]2[cH:23]1.[F:1][c:2]1[c:3]([CH:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:4][cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3]([CH:8]2[CH2:9][CH2:10][N:11]([C:24]([c:19]3[c:18]4[cH:17][cH:16][c:15]([Cl:14])[cH:23][c:22]4[nH:21][cH:20]3)=[O:25])[CH2:12][CH2:13]2)[cH:4][cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-a3edaf6264f841a098186735d0860832
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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