Dichloromethane → Tert-butyl [1-benzyl-2-({2-chloro-6-[(methylsulfonyl)(propyl)amino]pyridin-4-yl}methoxy)-1-methylethyl]carbamate
Reaction equation
[Ag+:62].[Br:20][CH2:21][c:22]1[cH:23][c:24]([N:29]([S:30](=[O:31])(=[O:32])[CH3:33])[CH2:34][CH2:35][CH3:36])[n:25][c:26]([Cl:28])[cH:27]1.[C:37]([c:38]1[cH:39][cH:40][cH:41][c:42]([C:43]([CH3:44])([CH3:45])[CH3:46])[n:47]1)([CH3:48])([CH3:49])[CH3:50].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[C:8]([CH2:9][OH:10])([CH3:11])[NH:12][C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19].[Cl:51][CH2:52][Cl:53].[S:54]([O-:55])([C:56]([F:57])([F:58])[F:59])(=[O:60])=[O:61]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[C:8]([CH2:9][O:10][CH2:21][c:22]1[cH:23][c:24]([N:29]([S:30](=[O:31])(=[O:32])[CH3:33])[CH2:34][CH2:35][CH3:36])[n:25][c:26]([Cl:28])[cH:27]1)([CH3:11])[NH:12][C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-27c6fad2948046e8811327cb26cefe89
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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