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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 319749Generated: October 29, 2026

Hydrochloric Acid → 6-(4-Chloro-phenyl)-5-(2-methoxy-ethoxy)-pyrazine-2-carboxylic acid (1-hydroxymethyl-cyclopropyl)-amide

https://huagongshe.com/reaction/319749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-Chloro-N,N-2-trimethylpropenylamineHCID 640792—
Reactant(1-Aminocyclopropyl)methanolHCID 14146220—
Reactant6-(4-Chloro-phenyl)-5-(2-methoxy-ethoxy)-pyrazine-2-carboxylic acidHCID 68799009—
Product6-(4-Chloro-phenyl)-5-(2-methoxy-ethoxy)-pyrazine-2-carboxylic acid (1-hydroxymethyl-cyclopropyl)-amideHCID 68841479—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-0bdd2e247f494218bbc74be3354325c6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)