Sodium ion → Tert-butyl 4-(4-aminofuro[3,2-c]pyridin-3-yl)-2-methoxyphenylcarbamate

HRID 319981Notes

Reaction equation

HRID 319981 reaction equation
[Br:1][c:2]1[cH:3][o:4][c:5]2[c:6]1[c:7]([NH2:11])[n:8][cH:9][cH:10]2.[CH3:12][O:13][c:14]1[c:15]([NH:29][C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[cH:16][cH:17][c:18]([B:20]2[O:21][C:22]([CH3:23])([CH3:24])[C:25]([CH3:26])([CH3:27])[O:28]2)[cH:19]1.[CH3:43][O:44][CH2:45][CH2:46][O:47][CH3:48].[Na+:37].[Na+:38].[O-:39][C:40](=[O:41])[O-:42].[OH2:49]>>[c:2]1(-[c:18]2[cH:17][cH:16][c:15]([NH:29][C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[c:14]([O:13][CH3:12])[cH:19]2)[cH:3][o:4][c:5]2[c:6]1[c:7]([NH2:11])[n:8][cH:9][cH:10]2

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 177502214-(tert-Butoxycarbonylamino)-3-methoxyphenylboronic acid, pinacol esterHCID 184507953-Bromofuro[3,2-c]pyridin-4-amine

Product 1

HCID 18451465Tert-butyl 4-(4-aminofuro[3,2-c]pyridin-3-yl)-2-methoxyphenylcarbamate

Sources & evidence

ORD record
ord-a4b05608baf647a7ae0634a83415aa12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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