1-Cyclopropyl-3-ethoxycarbonyl-7,8-difluoro-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine → (RS)-1-Cyclopropyl-3-ethoxycarbonyl-7-fluoro-8-[3-(2-furyl)-1-piperazinyl]-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine
Reaction equation
[CH:1]1([n:4]2[cH:5][c:6]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:7](=[O:20])[c:8]3[cH:9][c:10]4[c:11]([n:12][c:13]23)[cH:14][c:15]([F:19])[c:16]([F:18])[cH:17]4)[CH2:2][CH2:3]1.[o:26]1[c:27]([CH:31]2[NH:32][CH2:33][CH2:34][NH:35][CH2:36]2)[cH:28][cH:29][cH:30]1>>[CH:1]1([n:4]2[cH:5][c:6]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:7](=[O:20])[c:8]3[cH:9][c:10]4[c:11]([n:12][c:13]23)[cH:14][c:15]([N:35]2[CH2:34][CH2:33][NH:32][CH:31]([c:27]3[o:26][cH:30][cH:29][cH:28]3)[CH2:36]2)[c:16]([F:18])[cH:17]4)[CH2:2][CH2:3]1Participants
3
Sources & evidence
- ORD record
- ord-3c1f9992d03c418e936793bd82b6aa4b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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