反应详情

To a solution of (6-hydroxymethyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-carbamic acid tert-butyl ester (3.1 g, 11.18 mmol) in CH2Cl2 (30 mL) was added MnO2 (4.85 g, 55.9 mmol). The resulting mixture was stirred at RT under N2 gas for 18 h. Solvent was separated from MnO2 by passing through the Celite®. Solvent was evaporated in vacuo to give the final product. MS m/z: 276.5 (M+H). Calc'd. for C16H21NO3-275.34.

1. customSolvent was separated from MnO2
2. customSolvent was evaporated in vacuo