Methanol → 4-(5-Fluoro-2-methoxyphenyl)-4-methyl-2-trifluoromethyl-1-(2-(trifluoromethyl)-quinolin-5-ylamino)pentan-2-ol
Reaction equation
[BH4-:36].[CH3:38][OH:39].[F:1][c:2]1[cH:3][cH:4][c:5]([O:34][CH3:35])[c:6]([C:8]([CH2:9][C:10]([CH:11]=[N:12][c:13]2[c:14]3[cH:15][cH:16][c:17]([C:23]([F:24])([F:25])[F:26])[n:18][c:19]3[cH:20][cH:21][cH:22]2)([OH:27])[C:28]([F:29])([F:30])[F:31])([CH3:32])[CH3:33])[cH:7]1.[Na+:37]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:34][CH3:35])[c:6]([C:8]([CH2:9][C:10]([CH2:11][NH:12][c:13]2[c:14]3[cH:15][cH:16][c:17]([C:23]([F:24])([F:25])[F:26])[n:18][c:19]3[cH:20][cH:21][cH:22]2)([OH:27])[C:28]([F:29])([F:30])[F:31])([CH3:32])[CH3:33])[cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-62fd30d68c3e4fd89d5017ceaa6bfd77
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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