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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 321194Generated: October 26, 2026

Tetrahydrofuran → Methyl 2-cyanomethyl-2-phenylmethylbutanoate

https://huagongshe.com/reaction/321194

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantBromoacetonitrileHCID 11534—
ReactantHexamethylphosphoramideHCID 12679—
ReactantLithium ionHCID 28486—
ReactantDiisopropylamideHCID 5062348—
ReactantMethyl 2-phenylmethylbutyrateHCID 12647073—
ProductMethyl 2-cyanomethyl-2-phenylmethylbutanoateHCID 10609559—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-153cf99a0d294e3393f5c11456ec8b4a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)