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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 321195Generated: October 25, 2026

Chloride → Racemic (5-chloropyridin-2-yl)(cyclohexyl)(3-fluoro-5-(trifluoromethyl)phenyl)methanamine

https://huagongshe.com/reaction/321195

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantChlorotrimethylsilaneHCID 6397—
ReactantTetrahydrofuranHCID 8028—
Reactant3-Bromo-5-fluorobenzotrifluorideHCID 2736323—
Reactant5-Chloro-2-cyanopyridineHCID 3833942—
ReactantButyllithiumHCID 178418339—
ReactantHCID 178507034HCID 178507034—
ProductRacemic (5-chloropyridin-2-yl)(cyclohexyl)(3-fluoro-5-(trifluoromethyl)phenyl)methanamineHCID 58921044—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-85d585c8dae84a44bcf916d0c172d8eb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)