[2-Chloro-4-(trifluoromethyl)phenyl]boronic acid → Tert-butyl 13-[2-chloro-4-(trifluoromethyl)phenyl]-4,8-diazatetracyclo[6.6.1.02,7.011,15]pentadeca-1(14),11(15),12-triene-4-carboxylate

HRID 321309Notes

Reaction equation

HRID 321309 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]3[c:9]([cH:10]1)[CH2:11][CH2:12][N:7]3[CH:6]1[CH:5]2[CH2:16][N:15]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:14][CH2:13]1.[Cl:24][c:25]1[c:26]([B:35]([OH:36])[OH:37])[cH:27][cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1>>[c:2]1(-[c:26]2[c:25]([Cl:24])[cH:30][c:29]([C:31]([F:32])([F:33])[F:34])[cH:28][cH:27]2)[cH:3][c:4]2[c:8]3[c:9]([cH:10]1)[CH2:11][CH2:12][N:7]3[CH:6]1[CH:5]2[CH2:16][N:15]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 2783251[2-Chloro-4-(trifluoromethyl)phenyl]boronic acidHCID 178451541HCID 178451541, compound

Product 1

HCID 9891271Tert-butyl 13-[2-chloro-4-(trifluoromethyl)phenyl]-4,8-diazatetracyclo[6.6.1.02,7.011,15]pentadeca-1(14),11(15),12-triene-4-carboxylate

Sources & evidence

ORD record
ord-b3fe10fedd1442258bcf801ceed40846
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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