Methanol → Tert-butyl 3-[(2,3-difluorophenyl)-(2-hydroxyethoxy)methyl]piperidine-1-carboxylate
Reaction equation
[BH4-:30].[CH3:32][OH:33].[F:1][c:2]1[c:3]([CH:9]([CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[O:23][CH2:24][C:25](=[O:26])[O:27][CH2:28][CH3:29])[cH:4][cH:5][cH:6][c:7]1[F:8].[Na+:31]>>[F:1][c:2]1[c:3]([CH:9]([CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[O:23][CH2:24][CH2:25][OH:26])[cH:4][cH:5][cH:6][c:7]1[F:8]Participants
5
Sources & evidence
- ORD record
- ord-3546adcb2e3a4f4a848b76308dda97da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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