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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 321574Generated: October 25, 2026

Dimethylformamide → 4-(4-Dimethylcarbamoyl-3-fluoro-phenoxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid (5-methyl-isoxazol-3-yl)-amide

https://huagongshe.com/reaction/321574

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
Reactant4-(Dimethylamino)pyridineHCID 14284—
ReactantThionyl ChlorideHCID 24386—
Reactant3-Amino-5-methylisoxazoleHCID 66172—
Reactant4-(4-Dimethylcarbamoyl-3-fluoro-phenoxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acidHCID 59560411—
Product4-(4-Dimethylcarbamoyl-3-fluoro-phenoxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid (5-methyl-isoxazol-3-yl)-amideHCID 59560081—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-45765e065c1f4d93b35650667854465b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)