3-Cyclopropyl-2-hydroxypropanoic acid → 3-Cyclopropyl-2-[3-(3-fluorophenyl)-4-[[4-[3-(4-fluorophenyl)propyl]piperidin-1-yl]methyl]pyrrolidin-1-yl]propanoic acid
Reaction equation
[F:10][c:11]1[cH:12][cH:13][c:14]([CH2:17][CH2:18][CH2:19][CH:20]2[CH2:21][CH2:22][N:23]([CH2:26][CH:27]3[CH2:28][N:29]([CH:39]([C:40](=[O:41])[OH:42])[CH2:43][CH:44]4[CH2:45][CH2:46][CH2:48][CH2:47]4)[CH2:30][CH:31]3[c:32]3[cH:33][c:34]([F:38])[cH:35][cH:36][cH:37]3)[CH2:24][CH2:25]2)[cH:15][cH:16]1.[OH:1][CH:2]([CH2:3][CH:4]1[CH2:5][CH2:6]1)[C:7]([OH:8])=[O:9]>>[F:10][c:11]1[cH:12][cH:13][c:14]([CH2:17][CH2:18][CH2:19][CH:20]2[CH2:21][CH2:22][N:23]([CH2:26][CH:27]3[CH2:28][N:29]([CH:39]([C:40](=[O:41])[OH:42])[CH2:43][CH:44]4[CH2:45][CH2:46]4)[CH2:30][CH:31]3[c:32]3[cH:33][c:34]([F:38])[cH:35][cH:36][cH:37]3)[CH2:24][CH2:25]2)[cH:15][cH:16]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3a16839c967447248e7084aa719591e7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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