Potassium Cation → 3-[8-Amino-1-(3-benzyloxy-phenyl)-imidazo[1,5-a]pyrazin-3-yl]cyclobutanecarbaldehyde

HRID 321623Notes

Reaction equation

HRID 321623 reaction equation
[CH2:1]([Cl:2])[Cl:3].[CH2:4]([c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[O:11][c:12]1[cH:13][c:14](-[c:18]2[n:19][c:20]([CH:28]3[CH2:29][C:30](=[CH:32][O:33][CH3:34])[CH2:31]3)[n:21]3[c:22]2[c:23]([NH2:27])[n:24][cH:25][cH:26]3)[cH:15][cH:16][cH:17]1.[K+:35].[K+:36].[O-:37][C:38]([O-:39])=[O:40].[OH2:41]>>[CH2:4]([c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[O:11][c:12]1[cH:13][c:14](-[c:18]2[n:19][c:20]([CH:28]3[CH2:29][CH:30]([CH:32]=[O:33])[CH2:31]3)[n:21]3[c:22]2[c:23]([NH2:27])[n:24][cH:25][cH:26]3)[cH:15][cH:16][cH:17]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 111541581-(3-Benzyloxy-phenyl)-3-(3-methoxymethylene-cyclobutyl)-imidazo[1,5-a]pyrazin-8-ylamine

Product 1

HCID 112465273-[8-Amino-1-(3-benzyloxy-phenyl)-imidazo[1,5-a]pyrazin-3-yl]cyclobutanecarbaldehyde

Sources & evidence

ORD record
ord-1f29585ab27949a8a683745c504d176f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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