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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 321691Generated: October 25, 2026

Dichloromethane → 5-[[4-(Tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-(tetrahydro-pyran-2-yloxy)-methyl]-2-fluoro-benzonitrile

https://huagongshe.com/reaction/321691

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant3,4-dihydro-2H-pyranHCID 8080—
ReactantToluenesulfonateHCID 3424274—
ReactantPyridiniumHCID 4989215—
Reactant5-{[4-(Tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-hydroxy-methyl}-2-fluoro-benzonitrileHCID 137329419—
Product5-[[4-(Tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-(tetrahydro-pyran-2-yloxy)-methyl]-2-fluoro-benzonitrileHCID 137329418—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ac83243ca8904211ac08e517f67d8a5e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)