3-(Chloromethyl)-5-(3,5-difluorophenyl)-1,2,4-oxadiazole → 1-{[5-(3,5-Difluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}-3-fluoro-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 321702Notes

Reaction equation

HRID 321702 reaction equation
[Cl:18][CH2:19][c:20]1[n:21][o:22][c:23](-[c:25]2[cH:26][c:27]([F:32])[cH:28][c:29]([F:31])[cH:30]2)[n:24]1.[F:1][c:2]1[c:3]([CH3:17])[nH:4][c:5]2[cH:6][cH:7][c:8]([C:15]#[N:16])[c:9]([C:11]([F:12])([F:13])[F:14])[c:10]12>>[F:1][c:2]1[c:3]([CH3:17])[n:4]([CH2:19][c:20]2[n:21][o:22][c:23](-[c:25]3[cH:26][c:27]([F:32])[cH:28][c:29]([F:31])[cH:30]3)[n:24]2)[c:5]2[cH:6][cH:7][c:8]([C:15]#[N:16])[c:9]([C:11]([F:12])([F:13])[F:14])[c:10]12

Participants

3

Reactant 2

HCID 431202093-(Chloromethyl)-5-(3,5-difluorophenyl)-1,2,4-oxadiazoleHCID 578003103-fluoro-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 578005121-{[5-(3,5-Difluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}-3-fluoro-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-4235c9eed7544ab3a28f89f036d2d8bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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