Methanesulfonate → 1'-[4-(2-chloro-5-trifluoromethylbenzoyl)-1-butyl]-spiro[isobenzofuran-1(3H),4'-piperidine]
Reaction equation
[CH3:19][S:20](=[O:21])(=[O:22])[O-:23].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[CH2:6][CH2:7][CH2:8][CH2:9][OH:10])[cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]1.[NH:24]1[CH2:25][CH2:26][C:27]2([O:28][CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][c:35]32)[CH2:36][CH2:37]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[CH2:6][CH2:7][CH2:8][CH2:9][N:24]2[CH2:25][CH2:26][C:27]3([O:28][CH2:29][c:30]4[cH:31][cH:32][cH:33][cH:34][c:35]43)[CH2:36][CH2:37]2)[cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-56ea1f0913d04c05831eff87662a545f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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