Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Calcium Acetate → 2-Acetylbenzofuran-monohydrazone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Calcium Acetate | HCID 6116 | — |
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | 4-(Dimethylamino)Benzaldehyde | HCID 7479 | — |
| 반응물 | Potassium Acetate | HCID 517044 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | HCID 54310932 | HCID 54310932 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-Acetylbenzofuran-monohydrazone | HCID 73180426 | — |
반응 단계
In formulae (XVII), (XVIII), (XIX), (XX) and (VII), Ar1, Ar2, Ar3, Ar4, R1, a and n have the same meaning as described above. A 2-acetylformylbenzofuran compound represented by formula (XVII) (1.0 equivalent) and a hydrazine reagent represented by formula (XVIII) (0.95 to 1.00 equivalent) are heated and stirred in an organic solvent, such as ethanol, methanol, tetrahydrofuran, 1,4-dioxane and acetonitrile, to which a catalyst (0.001 to 0.01 equivalent), such as acetic acid, potassium acetate, calcium acetate and sodium acetate, is added, at about 40 to 50° C. for about 3 to 10 hours, so as to obtain a 2-acetylbenzofuran-monohydrazone compound represented by formula (XIX).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06210847B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-9bdccff19edd4177aaf4aeec32e3c87f |
| 출처 메모 | uspto-grants-2001_04 |