HCID 10823223, compound → HCID 15523793, compound
Reaction equation
[C:1]1([S:7][CH2:8][CH:9]2[NH:12][C:11](=[O:13])[CH2:10]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1([O:20][C:21](=O)[NH:22][CH2:23][C:24]2[CH:29]=[CH:28][N:27]=[CH:26][CH:25]=2)C=CC=CC=1>>[N:27]1[CH:28]=[CH:29][C:24]([CH2:23][NH:22][C:21]([N:12]2[C@@H:9]([CH2:8][S:7][C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)[CH2:10][C:11]2=[O:13])=[O:20])=[CH:25][CH:26]=1Participants
3
Procedure
Following the same procedure as in example 4, step D, but using 4-(phenylsulfanylmethyl)azetidin-2-one and (pyridin-4-ylmethyl)carbamic acid phenyl ester as reactants gave 2-oxo-4(R)-(phenylsulfanylmethyl)azetidine-1-carboxylic acid (pyridin-4-ylmethyl)amide as a white solid.
Sources & evidence
- ORD record
- ord-48777a9d563b482da20a91a3aa6a2f3b
- Source dataset
- uspto-grants-2001_04
- Patent number
- US06211170B1
Reaction notes
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