HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Amino-4-[4-(3-Pyridyl)Anilino]-3-Cyclobutene-1,2-Dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-(Pyridin-3-yl)aniline | HCID 459522 | — |
| Reactant | 3-Amino-4-ethoxycyclobut-3-ene-1,2-dione | HCID 15146336 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3-Amino-4-[4-(3-Pyridyl)Anilino]-3-Cyclobutene-1,2-Dione | HCID 9816757 | 41.8% |
Reaction Steps
A solution of 3-(4-aminophenyl)pyridine (0.51 g) and 3-amino-4-ethoxy-3-cyclobutene 1,2-dione (0.42 g) in pyridine (2 ml) is stirred at 80° for 20 hours. The cool mixture is treated with water (15 ml), and the solid filtered off and washed with water and hot methanol. Recrystallation from dimethylformamide gives 0.33 g of the title compound, mp 3224° C. dec.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211220B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-aa05ba3bd85e44dba5f6ce3a32446e72 |
| Source note | uspto-grants-2001_04 |