HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Amino-4-[6-(4-Pyridyl)-2-Pyridylamino]-3-Cyclobutene-1,2-Dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-Amino-4-n-butoxy-3-cyclobutene-1,2-dione | HCID 14545034 | — |
| Reactant | 6-(Pyridin-4-yl)pyridin-2-amine | HCID 14964571 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3-Amino-4-[6-(4-Pyridyl)-2-Pyridylamino]-3-Cyclobutene-1,2-Dione | HCID 22009935 | 13.8% |
Reaction Steps
A stirred solution of 2-amino-6-(4-pyridyl)pyridine (0.34 g) and 3-amino-4-n-butoxy-3-cyclobutene-1,2-dione (0.34 g) in pyridine (2 ml) is heated under reflux for 8 hours. The cool mixture is treated with water (15 ml) and the mixture stirred for 1 hour. The solid is filtered, washed with water, ethanol and ether, charcoaled and recrystallised from dimethylformamide to give 73 mg of the title compound, mp >340° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211220B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-ef7a3c74db45479892f0006a858ed7bd |
| Source note | uspto-grants-2001_04 |