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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322241Generated: October 27, 2026

Methanesulfonyl chloride → 3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonate

https://huagongshe.com/reaction/322241

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propanolHCID 15521671—
Product3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonateHCID 1552167492%

Reaction Steps

In substantially the same manner as in Reference Example 12, 3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propanol was allowed to react with methanesulfonyl chloride to give 3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonate. The yield was 92%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 111-112° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-89974e039da2451a9d643df68127281c
Source noteuspto-grants-2001_04