HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 4-Chlorobenzamide | HCID 12084 | — |
| Product | 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole | HCID 7131527 | 54% |
Reaction Steps
In substantially the same manner as in Reference Example 31, 4-chlorobenzamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(4-chlorophenyl)oxazole. The yield was 54%. Recrystallization from isopropyl ether gave colorless needles, mp 97-98° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-82d83f571a7c4a0bb240f7784ecb169d |
| Source note | uspto-grants-2001_04 |