HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → 2-(4-Benzyloxy-phenyl)-4-chloromethyl-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 4-Benzyloxybenzamide | HCID 2726431 | — |
| Product | 2-(4-Benzyloxy-phenyl)-4-chloromethyl-oxazole | HCID 22009845 | 33% |
Reaction Steps
In substantially the same manner as in Reference Example 31, 4-benzyloxybenzamide was allowed to react with 1,3-dichloroacetone to give 2-(4-benzyloxyphenyl)-4-chloromethyloxazole. The yield was 33%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 119-120° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-c866ceb1ade34cdda156129c141a786c |
| Source note | uspto-grants-2001_04 |