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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322267Generated: October 26, 2026

1,3-Dichloroacetone → 4-(Chloromethyl)-2-cyclohexyl-1,3-oxazole

https://huagongshe.com/reaction/322267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DichloroacetoneHCID 10793—
ReactantCyclohexanecarboxamideHCID 14283—
Product4-(Chloromethyl)-2-cyclohexyl-1,3-oxazoleHCID 222413792.7%

Reaction Steps

In substantially the same manner as in Reference Example 31, cyclohexanecarboxamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-cyclohexyloxazole as an oily product. The yield was 2.7%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-d7254fecd64b4a98a96fe9f4615ee5dd
Source noteuspto-grants-2001_04