1,3-Dichloroacetone → HCID 22009737, compound

HRID 322272Notes

Reaction equation

HRID 322272 reaction equation
[C:1]1([C:7]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:8][C:9]([NH2:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:18][CH2:19][C:20]([CH2:22]Cl)=O>>[C:1]1([C:7]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:8][C:9]2[O:10][CH:22]=[C:20]([CH2:19][Cl:18])[N:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 107931,3-DichloroacetoneHCID 12632083HCID 12632083, compound

Product 1

HCID 22009737HCID 22009737, compoundYield 49%

Procedure

In substantially the same manner as in Reference Example 31, 3,3-diphenylpropenamide was allowed to react with 1,3-dichloroacetone to give 2-(2,2-diphenylethenyl)-4-chloromethyloxazole. The yield was 49%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 107-108° C.

Sources & evidence

ORD record
ord-f302227b83254d2ba9dbcd1e217a9916
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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