1,3-Dichloroacetone → HCID 22009682, compound

HRID 322275Notes

Reaction equation

HRID 322275 reaction equation
[CH:1]1([CH:7]=[CH:8][C:9]([NH2:11])=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:12][CH2:13][C:14]([CH2:16]Cl)=O>>[Cl:12][CH2:13][C:14]1[N:11]=[C:9](/[CH:8]=[CH:7]/[CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[O:10][CH:16]=1

Participants

3

Reactant 2

HCID 107931,3-DichloroacetoneHCID 54292987HCID 54292987, compound

Product 1

HCID 22009682HCID 22009682, compoundYield 4.5%

Procedure

In substantially the same manner as in Reference Example 47, 3-cyclohexylpropeneamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-[(E)-2-cyclohexylethenyl]oxazole. The yield was 4.5%. Oily substance.

Sources & evidence

ORD record
ord-98bc3c92eb1f421a91157f3849c8f165
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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