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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322286Generated: October 29, 2026

1,3-Dichloroacetone → HCID 54281256, compound

https://huagongshe.com/reaction/322286

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DichloroacetoneHCID 10793—
Reactant4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamideHCID 12231507—
ProductHCID 54281256HCID 5428125653%

Reaction Steps

In substantially the same manner as in Reference Example 47, 4,5,6,7-tetrahydro-2-benzothiophene carboxamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(4,5,6,7-tetrahydro-2-benzothienyl)oxazole. The yield was 53%. Recrystallization from ethyl acetate-hexane gave colorless needles, mp 102-103° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-36c11933e0ce4a4cbef9f2b862d493cf
Source noteuspto-grants-2001_04