1,3-Dichloroacetone → HCID 22009833, compound

HRID 322288Notes

Reaction equation

HRID 322288 reaction equation
[Cl:1][C:2]1[O:6][C:5]([C:7]([NH2:9])=[O:8])=[CH:4][CH:3]=1.[Cl:10][CH2:11][C:12]([CH2:14]Cl)=O>>[Cl:1][C:2]1[O:6][C:5]([C:7]2[O:8][CH:14]=[C:12]([CH2:11][Cl:10])[N:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 107931,3-DichloroacetoneHCID 13092470HCID 13092470, compound

Product 1

HCID 22009833HCID 22009833, compoundYield 24%

Procedure

In substantially the same manner as in Reference Example 47, 5-chloro-2-furancarboxamide was allowed to react with 1,3-dichloroacetone to give 2-(5-chloro-2-furyl)-4-chloromethyloxazole. The yield was 24%. Recrystallization from diethyl ether-hexane gave colorless prisms, mp 107-108° C.

Sources & evidence

ORD record
ord-4da3aa0e0fb2437f9c734acce1f026be
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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