Imidazole → HCID 22009738, compound

HRID 322312Notes

Reaction equation

HRID 322312 reaction equation
CS(O[CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([O:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:11]=1)(=O)=O.[NH:24]1[CH:28]=[CH:27][N:26]=[CH:25]1>>[CH2:17]([O:16][C:12]1[CH:11]=[C:10]([CH2:9][CH2:8][CH2:7][CH2:6][N:24]2[CH:28]=[CH:27][N:26]=[CH:25]2)[CH:15]=[CH:14][CH:13]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 22009796HCID 22009796, compound

Product 1

HCID 22009738HCID 22009738, compoundYield 61%

Procedure

In substantially the same manner as in Reference Example 88, 4-(3-benzyloxyphenyl)butyl methanesulfonate was allowed to react with imidazole to give 1-[4-(3-benzyloxyphenyl)butyl]imidazole. The yield was 61%. Oily substance.

Sources & evidence

ORD record
ord-2e01a91b0d224949a23302552237398f
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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