Hydride → HCID 22009647, compound

HRID 322324Notes

Reaction equation

HRID 322324 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][CH:8]=[C:9]([CH2:11][C:12](OCC)=[O:13])[N:10]=1.[Li].[H-]>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][CH:8]=[C:9]([CH2:11][CH2:12][OH:13])[N:10]=1

Participants

4

Reactant 3

HCID 166653HydrideHCID 3028194LithiumHCID 54507046HCID 54507046, compound

Product 1

HCID 22009647HCID 22009647, compoundYield 73%

Procedure

In substantially the same manner as in Reference Example 72. ethyl 2-(2-thienyl)-4-oxazolylacetate was subjected to reduction with lithium alminum hydride to obtain 2-[2-(2-thienyl)-4-oxazolyl]ethanol as an oil. The yield was 73%.

Sources & evidence

ORD record
ord-4f27fb3c6e6c498d806789cc95f3cc75
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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