Hydride → HCID 22009694, compound

HRID 322325Notes

Reaction equation

HRID 322325 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][CH:8]=[C:9]([CH2:11][CH2:12][C:13](OCC)=[O:14])[N:10]=1.[Li].[H-]>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][CH:8]=[C:9]([CH2:11][CH2:12][CH2:13][OH:14])[N:10]=1

Participants

4

Reactant 3

HCID 166653HydrideHCID 3028194LithiumHCID 22009607HCID 22009607, compound

Product 1

HCID 22009694HCID 22009694, compoundYield 97%

Procedure

In substantially the same manner as in Reference Example 72, ethyl 3-[2-(2-thienyl)-4-oxazolyl]propionate was subjected to reduction with lithium alminum hydride to obtain 3-[2-(2-thienyl)-4-oxazolyl]propanol as an oil. The yield was 97%.

Sources & evidence

ORD record
ord-294770a3c86f4d3c83b7d446df4348ee
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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