Imidazole → HCID 22009734, compound

HRID 322336Notes

Reaction equation

HRID 322336 reaction equation
CS(O[CH2:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:11]([O:23][CH3:24])[CH:10]=1)(=O)=O.[NH:25]1[CH:29]=[CH:28][N:27]=[CH:26]1>>[CH2:16]([O:15][C:12]1[CH:13]=[CH:14][C:9]([CH2:8][CH2:7][CH2:6][N:25]2[CH:29]=[CH:28][N:27]=[CH:26]2)=[CH:10][C:11]=1[O:23][CH3:24])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 22009606HCID 22009606, compound

Product 1

HCID 22009734HCID 22009734, compoundYield 57%

Procedure

In substantially the same manner as in Reference Example 88, 3-(4-benzyloxy-3-methoxyphenyl)propyl methanesulfonate was reacted with imidazole to obtain 1-[3-(4-benzyloxy-3-methoxyphenyl)propyl]imidazole as an oil. The yield was 57%.

Sources & evidence

ORD record
ord-88c044bd556940cdb7b752348b63afdc
Source dataset
uspto-grants-2001_04
Patent number
US06211215B1

Reaction notes

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