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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322356Generated: October 29, 2026

Benzimidazole → 1-[4-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]butyl]benzimidazole

https://huagongshe.com/reaction/322356

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzimidazoleHCID 5798—
Reactant4-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]butyl methanesulfonateHCID 15521676—
Product1-[4-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]butyl]benzimidazoleHCID 2200981536%

Reaction Steps

In substantially the same manner as in Working Example 8, benzimidazole was allowed to react with 4-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]butyl methanesulfonate to give 1-[4-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]butyl]benzimidazole. The yield was 36%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 148-149° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-0fbaba7c39c94001a1c47cc1e316c99e
Source noteuspto-grants-2001_04