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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322363Generated: October 27, 2026

Benzimidazole → 1-[3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]benzimidazole

https://huagongshe.com/reaction/322363

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzimidazoleHCID 5798—
Reactant3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonateHCID 15521674—
Product1-[3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]benzimidazoleHCID 2200973349%

Reaction Steps

In substantially the same manner as in Working Example 25, 3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonate was allowed to react with benzimidazole to give 1-[3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]benzimidazole. The yield was 49%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 115-117° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-d4d10fab51154499af0237fa7aef042f
Source noteuspto-grants-2001_04