反应详情

In substantially the same manner as in Working Example 48, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 2-(3-benzyloxyphenyl)-4-chloromethyloxazole to give 2-(3-benzyloxyphenyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole. The yield was 65%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 112-113° C.