HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[3-(3-Hydroxyphenyl)propyl]imidazole → 4-[3-[3-(1-Imidazolyl)propyl]phenoxymethyl]-2-(5-methyl-2-thienyl)oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[3-(3-Hydroxyphenyl)propyl]imidazole | HCID 22009809 | — |
| Reactant | 4-Chloromethyl-2-(5-methyl-2-thienyl)oxazole | HCID 22241454 | — |
| Product | 4-[3-[3-(1-Imidazolyl)propyl]phenoxymethyl]-2-(5-methyl-2-thienyl)oxazole | HCID 22009847 | 71% |
Reaction Steps
In substantially the same manner as in Working Example 72, 1-[3-(3-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(5-methyl-2-thienyl)oxazole to give 4-[3-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-(5-methyl-2-thienyl)oxazole. The yield was 71%. Oily substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-27cadd954af94d35b9f6f17d89f2d7f8 |
| Source note | uspto-grants-2001_04 |