HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-2-phenyl-1,3-thiazole → HCID 22009868, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-2-phenyl-1,3-thiazole | HCID 236969 | — |
| Reactant | 1-[3-(4-Hydroxyphenyl)propyl]imidazole | HCID 22009818 | — |
| Product | HCID 22009868 | HCID 22009868 | 78% |
Reaction Steps
In substantially the same manner as in Working Example 72, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-phenylthiazole to give 4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-phenylthiazole. The yield was 78%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 110-111° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-8e1b0ca2061542cb8f3eb46714398bc5 |
| Source note | uspto-grants-2001_04 |