反应详情

In substantially the same manner as in Working Example 72, 1-[4-(4-hydroxyphenyl)butyl]imidazole was allowed to react with 4-chloromethyl-2-phenylthiazole to give 4-[4-[4-(1-imidazolyl)butyl]phenoxymethyl]-2-phenylthiazole. The yield was 91%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 93-94° C.