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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322431Generated: October 30, 2026

HCID 22009653, compound → 4-[4-[3-(1-Imidazolyl)propyl]phenoxymethyl]-2-(3-thienyl)oxazole

https://huagongshe.com/reaction/322431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22009653HCID 22009653—
Reactant1-[3-(4-Hydroxyphenyl)propyl]imidazoleHCID 22009818—
Product4-[4-[3-(1-Imidazolyl)propyl]phenoxymethyl]-2-(3-thienyl)oxazoleHCID 2200970765%

Reaction Steps

In substantially the same manner as in Working Example 109, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(3-thienyl)oxazole to give 4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-(3-thienyl)oxazole. The yield was 65%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 102-103° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-3f979d2684ad4d6e8bbe217caa36f3f5
Source noteuspto-grants-2001_04