HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Benzyloxy)-5-(chloromethyl)pyridine → HCID 22009764, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Benzyloxy)-5-(chloromethyl)pyridine | HCID 22009600 | — |
| Reactant | 1-[3-(4-Hydroxyphenyl)propyl]imidazole | HCID 22009818 | — |
| Product | HCID 22009764 | HCID 22009764 | 65% |
Reaction Steps
In substantially the same manner as in Working Example 109, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 2-benzyloxy-5-chloromethylpyridine to give 2-benzyloxy-5-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]pyridine. The yield was 65%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 84-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-cb78e9ee10624c06a40b5d13e2c0468a |
| Source note | uspto-grants-2001_04 |