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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322444Generated: October 25, 2026

1-[4-(4-Hydroxyphenyl)butyl]imidazole → HCID 22009773, compound

https://huagongshe.com/reaction/322444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(4-Hydroxyphenyl)butyl]imidazoleHCID 22009664—
Reactant2-(4-Benzyloxy-phenyl)-4-chloromethyl-oxazoleHCID 22009845—
ProductHCID 22009773HCID 2200977354%

Reaction Steps

In substantially the same manner as in Working Example 109, 1-[4-(4-hydroxyphenyl)butyl]imidazole was allowed to react with 2-(4-benzyloxyphenyl)-4-chloromethyloxazole to give 2-(4-benzyloxyphenyl)-4-[4-[4-(1-imidazolyl)butyl]phenoxymethyl]oxazole. The yield was 54%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 118-120° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211215B1
Source datasetuspto-grants-2001_04
ORD IDord-2e2fd6fbf2b944af94d7fdc5629f1ef7
Source noteuspto-grants-2001_04