HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(chloromethyl)-3-(2-thienyl)-1,2,4-oxadiazole → HCID 22009758, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(chloromethyl)-3-(2-thienyl)-1,2,4-oxadiazole | HCID 736830 | — |
| Reactant | 1-[4-(4-Hydroxyphenyl)butyl]imidazole | HCID 22009664 | — |
| Product | HCID 22009758 | HCID 22009758 | 29% |
Reaction Steps
In substantially the same manner as in Working Example 72, 1-[4-(4-hydroxyphenyl)butyl]imidazole was reacted with 5-chloromethyl-3-(2-thienyl)-1,2,4-oxadiazole to obtain 5-[4-[4-(1-imidazolyl)butyl]phenoxymethyl]-3-(2-thienyl)-1,2,4-oxadiazole. The yield was 29%. Recrystallization from a ethyl acetate-MeOH gave colorless prisms, mp 94-95° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211215B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-ac8b18f1e7bf4983a288b60a0c94b46f |
| Source note | uspto-grants-2001_04 |