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HRID322583

反应详情

EQUATION

反应方程式

HRID 322583 的结构方程式

REACTANTS

反应物

4
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：CC(C)c1ccc(C=CC#N)cc1
HCID4319058

未命名化合物

结构：COc1cccc([C@@H](C)N)c1
HCID7020759

(R)-1-(3-Methoxyphenyl)ethylamine

C9H13NO

结构：CC(C)[CH2][Al+][CH2]C(C)C.[H-]
HCID21225700

未命名化合物

PRODUCTS

生成物

1
结构：COc1cccc([C@@H](C)NCC=Cc2ccc(C(C)C)cc2)c1
HCID53750765

未命名化合物

PROCEDURE

实验过程

In a similar fashion, 4-isopropylcinnamonitrile was treated with diisobutyl aluminum hydride and the intermediate aluminum-imine complex treated with (R)-1-(3-methoxyphenyl)ethylamine. The intermediate imine was treated with ethanolic sodium borohydride. Work-up and chromatography yielded (R)-N-[3-(4-isopropylphenyl)prop-2-enyl]-1-(3-methoxyphenyl)ethylamine, 12E, as a clear, colorless oil; m/z (rel. int.) 309 (M+, 9), 294 (7),174 (98),159 (22),135 (80), 117 (100),105 (35), 91 (37), 77 (19).