HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 54282868, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | (R)-1-(3-Methoxyphenyl)ethylamine | HCID 7020759 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | 3-(3-Methylphenyl)-2-propenenitrile | HCID 54235565 | — |
| Product | HCID 54282868 | HCID 54282868 | — |
Reaction Steps
In a similar fashion, 3-methylcinnamonitrile was treated with diisobutyl aluminum hydride and the intermediate aluminum-imine complex treated with (R)-1-(3-methoxyphenyl)ethylamine. The intermediate imine was treated with ethanolic sodium borohydride. Work-up and chromatography yielded (R)-N-[3-(3-methylphenyl)prop-2-enyl]-1-(3-methoxyphenyl)ethylamine, 12G, as a clear, colorless oil; m/z (rel. int.) 281 (M+, 5), 266 (9), 176 (24), 146 (71), 135 (62), 131 (100), 115 (23), 105 (19), 91 (41), 77 (18).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211244B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-15df5bc1c9924190a1e1528e61b93c9d |
| Source note | uspto-grants-2001_04 |