HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylprop-2-enenitrile → HCID 54421245, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylprop-2-enenitrile | HCID 74667 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | (R)-1-(3-Methoxyphenyl)ethylamine | HCID 7020759 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Product | HCID 54421245 | HCID 54421245 | — |
Reaction Steps
In a similar fashion, cinnamonitrile was treated with diisobutyl aluminum hydride and the intermediate aluminum-imine complex treated with (R)-1-(3-methoxyphenyl)ethylamine. The intermediate imine was treated with ethanolic sodium borohydride. Work-up and chromatography yielded (R)-N-(3-phenylprop-2-enyl)-1-(3-methoxyphenyl)ethylamine, 25E, as a clear colorless oil; m/z (rel. int.) 267 (M+. 3), 252 (14),176 (17), 135 (62),117 (100), 105 (28), 91 (56), 77 (33).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211244B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-318ac4f5dbff4905b45da8985900cf0b |
| Source note | uspto-grants-2001_04 |