2-Acetylnaphthalene → N-[1-(2-naphthyl)ethyl]-1-(3-methoxyphenyl)ethylamine

Participants

Reaction Steps

In a similar fashion equal molar amounts 1-(3-methoxyphenyl)ethylamine (1.51 g, 10 mmol), 2′-acetonaphthone (1.70 g, 10 mmol) and 1.25 equivalents of titanium(IV) isopropoxide (3.55 g, 12.5 mmol) were treated as above. Work-up yielded N-[1-(2-naphthyl)ethyl]-1-(3-methoxyphenyl)ethylamine, 6F, as a clear, colorless oil; m/z (rel. int.) 305 (M+, 1), 290 (35), 170 (49), 155 (100), 135 (55), 115 (8), 105 (10), 91 (9), 77 (10).

Provenance & Evidence