Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322652Generated: October 25, 2026

3-Thiophenacetic acid → 2-((Thien-3-yl)acetamido]butyric acid iso-butyl ester

https://huagongshe.com/reaction/322652

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenacetic acidHCID 23404—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-((Thien-3-yl)acetamido]butyric acid iso-butyl esterHCID 54265759—

Reaction Steps

Following General Procedure I′ above and using 3-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tIc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211235B1
Source datasetuspto-grants-2001_04
ORD IDord-e9fb16452d294abfad632e651a5d42c2
Source noteuspto-grants-2001_04