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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322662Generated: October 25, 2026

Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/322662

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneacetic acid, 2-fluoro-HCID 67979—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl EsterHCID 53643249—

Reaction Steps

Following General Procedure I′ above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211235B1
Source datasetuspto-grants-2001_04
ORD IDord-35b9f3cf2726416790ab8462c69215f7
Source noteuspto-grants-2001_04