HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Thiophenacetic acid → N-[(3thienyl)acetyl]alanine Iso-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Thiophenacetic acid | HCID 23404 | — |
| Reactant | 2-methylpropyl (2S)-2-aminopropanoate | HCID 13743556 | — |
| Product | N-[(3thienyl)acetyl]alanine Iso-butyl Ester | HCID 53969374 | — |
Reaction Steps
Following General Procedure I′ above, and using 3-thiopheneacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure. NMR data was as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211235B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-d587ac8b4fd74ad7a0a200d2b791f07d |
| Source note | uspto-grants-2001_04 |